Gene Therapy Breakthroughs: The Future of Longevity & Health Optimization Artwork

The Pain and Performance Podcast

Scientifically Hacking: Health, Healing, Pain, Nutrition, and Longevity. We'll dive into all the exact habits, technology and recommendations you can use to optimize health, healing and life! Learn how I use and apply these everyday in my Pain Specialty Practice to improve my patient's lives, speed their healing, and increase longevity. On the podcast, I interview the scientist, doctors, creators and even patients on topics like: -Health Optimization-Supercharge Healing and Recovery-Sleep Enhancements Techniques-Daily Routines and Tactics for the Optimized Life-Research on Technology, Treatments, Supplements and more.-Case Review - We interview and discuss difficulty pain or health cases and how someone improved, healed and got back to living!-Mindset Improvements-Wholistic Living -Much, Much More!

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The Pain and Performance Podcast

Gene Therapy Breakthroughs: The Future of Longevity & Health Optimization

May 08, 2025 • Episode 157

In this episode of the Pain and Performance Podcast, I sit down with Mac Davis, the founder of Mini Circle, a cutting-edge company revolutionizing gene therapy with mini-circle plasmids. If you’ve ever wondered how science is pushing the boundaries of longevity, muscle growth, and inflammation control; this conversation is a must-listen.

"Health feels better than convenient."

What Makes Mini-Circle Plasmids Different?
Most gene therapy sounds like sci-fi, but Mini Circle’s approach is different; safer, cleaner, and non-invasive to your DNA. Unlike traditional methods that can alter your genetic code, mini-circle plasmids work alongside your body’s natural systems without changing your original blueprint.

No DNA modification – Just temporary instructions that help your body heal and optimize itself.

Delivered into fat tissue – Simple injections (no scary viral vectors).

Focused on real-world results – From reducing chronic pain to boosting muscle growth.

The Power of Folistatin: More Than Just Muscle
Folistatin isn’t some synthetic lab chemical; it’s a natural human hormone that regulates muscle growth, fat metabolism, and even bone health. But its real superpower? Fighting chronic inflammation, one of the biggest hidden killers in modern health.

Patients with stubborn joint pain and injuries report dramatic improvements after Folistatin therapy.

It’s not just for athletes; anyone dealing with age-related muscle loss or inflammation could benefit.

Clotho: The "Magic" Longevity Gene
If you haven’t heard of Clotho, pay attention. This gene therapy is showing insane potential for:

Cognitive function – Patients describe "brain fog" lifting within weeks.

Kidney health – A major factor in how well we age.

Overall vitality – Some say they feel "like their younger selves" again.

One of the most striking takeaways? A patient who said:
"This is how I was before. This is me."

Stacking Therapies for Maximum Impact
Why stop at one therapy when you can combine them? Gene therapy stacking (like using Folistatin + Clotho) could be the next big leap in health optimization. Think of it like building a personalized longevity protocol—tailored to your body’s needs.

People in their 50s and 60s regaining muscle and energy levels they hadn’t seen in decades.

Individuals prioritizing quality of life over just adding years.

As Mac puts it: "People deserve to be healthy."

Links:
DERRICK
TikTok:
https://www.tiktok.com/@drderrick
Instagram:
https://www.instagram.com/derrickbhines/
Youtube:
https://www.youtube.com/@DrDerrick

Mac Davis:
Website:
https://minicircle.io/
Instagram:
https://www.instagram.com/minicircledna/